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Full distance-resolved folding energy landscape of one single protein molecule

Kinetic bulk and single molecule folding experiments characterize barrier properties but the shape of folding landscapes between barrier top and native state is difficult to access. Here, we directly extract the full free energy landscape of a single molecule of the GCN4 leucine zipper using dual be...

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Bibliografske podrobnosti
Main Authors: Gebhardt, J. Christof M., Bornschlögl, Thomas, Rief, Matthias
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836620/
https://ncbi.nlm.nih.gov/pubmed/20133846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909854107
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