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Reconstructing folding energy landscapes from splitting probability analysis of single-molecule trajectories
Structural self-assembly in biopolymers, such as proteins and nucleic acids, involves a diffusive search for the minimum-energy state in a conformational free-energy landscape. The likelihood of folding proceeding to completion, as a function of the reaction coordinate used to monitor the transition...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4466695/ https://ncbi.nlm.nih.gov/pubmed/26039984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419490112 |
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