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Full distance-resolved folding energy landscape of one single protein molecule

Kinetic bulk and single molecule folding experiments characterize barrier properties but the shape of folding landscapes between barrier top and native state is difficult to access. Here, we directly extract the full free energy landscape of a single molecule of the GCN4 leucine zipper using dual be...

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Detalhes bibliográficos
Main Authors: Gebhardt, J. Christof M., Bornschlögl, Thomas, Rief, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836620/
https://ncbi.nlm.nih.gov/pubmed/20133846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909854107
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