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DNA/Amphiphilic Block Copolymer Nanospheres Promote Low-dose DNA Vaccination

Intramuscular (i.m.) DNA vaccination induces strong cellular immune responses in the mouse, but only at DNA doses that cannot be achieved in humans. Because antigen expression is weak after naked DNA injection, we screened five nonionic block copolymers of poly(ethyleneoxide)-poly(propyleneoxide) (P...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: McIlroy, Dorian, Barteau, Benoît, Cany, Jeannette, Richard, Peggy, Gourden, Clothilde, Conchon, Sophie, Pitard, Bruno
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835232/
https://ncbi.nlm.nih.gov/pubmed/19417740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.84
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