Amphiphilic block copolymers enhance the cellular uptake of DNA molecules through a facilitated plasma membrane transport

Amphiphilic block copolymers have been developed recently for their efficient, in vivo transfection activities in various tissues. Surprisingly, we observed that amphiphilic block copolymers such as Lutrol® do not allow the transfection of cultured cells in vitro, suggesting that the cell environmen...

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Detalhes bibliográficos
Main Authors: Chèvre, Raphaël, Le Bihan, Olivier, Beilvert, Fanny, Chatin, Benoit, Barteau, Benoit, Mével, Mathieu, Lambert, Olivier, Pitard, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Synthetic Biology and Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045598/
https://ncbi.nlm.nih.gov/pubmed/20952409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq922
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