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Probing the in vitro mechanism of action of cationic lipid/DNA lipoplexes at a nanometric scale

Cationic lipids are used for delivering nucleic acids (lipoplexes) into cells for both therapeutic and biological applications. A better understanding of the identified key-steps, including endocytosis, endosomal escape and nuclear delivery is required for further developments to improve their effic...

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Detalhes bibliográficos
Main Authors: Le Bihan, Olivier, Chèvre, Raphaël, Mornet, Stéphane, Garnier, Boris, Pitard, Bruno, Lambert, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045597/
https://ncbi.nlm.nih.gov/pubmed/21078679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq921
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