Amphiphilic block copolymers enhance the cellular uptake of DNA molecules through a facilitated plasma membrane transport

Amphiphilic block copolymers have been developed recently for their efficient, in vivo transfection activities in various tissues. Surprisingly, we observed that amphiphilic block copolymers such as Lutrol® do not allow the transfection of cultured cells in vitro, suggesting that the cell environmen...

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Detalles Bibliográficos
Autores principales: Chèvre, Raphaël, Le Bihan, Olivier, Beilvert, Fanny, Chatin, Benoit, Barteau, Benoit, Mével, Mathieu, Lambert, Olivier, Pitard, Bruno
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045598/
https://ncbi.nlm.nih.gov/pubmed/20952409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq922
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