Amphiphilic block copolymers enhance the cellular uptake of DNA molecules through a facilitated plasma membrane transport

Amphiphilic block copolymers have been developed recently for their efficient, in vivo transfection activities in various tissues. Surprisingly, we observed that amphiphilic block copolymers such as Lutrol® do not allow the transfection of cultured cells in vitro, suggesting that the cell environmen...

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Autors principals: Chèvre, Raphaël, Le Bihan, Olivier, Beilvert, Fanny, Chatin, Benoit, Barteau, Benoit, Mével, Mathieu, Lambert, Olivier, Pitard, Bruno
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Synthetic Biology and Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045598/
https://ncbi.nlm.nih.gov/pubmed/20952409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq922
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