Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

Chromosomal translocations involving the ERG locus are frequent events observed in human prostate cancer pathogenesis, however the biologic role of ERG aberrant expression is controversial.1 Here we demonstrate that the aberrant expression of ERG is a progression event in prostate tumorigenesis. We...

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Hlavní autoři: Carver, Brett S, Tran, Jennifer, Gopalan, Anuradha, Chen, Zhenbang, Shaikh, Safa, Carracedo, Arkaitz, Alimonti, Andrea, Nardella, Caterina, Varmeh, Shohreh, Scardino, Peter T, Cordon-Cardo, Carlos, Gerald, William, Pandolfi, Pier Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835150/
https://ncbi.nlm.nih.gov/pubmed/19396168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.370
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