Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

Chromosomal translocations involving the ERG locus are frequent events observed in human prostate cancer pathogenesis, however the biologic role of ERG aberrant expression is controversial.1 Here we demonstrate that the aberrant expression of ERG is a progression event in prostate tumorigenesis. We...

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Detalhes bibliográficos
Main Authors: Carver, Brett S, Tran, Jennifer, Gopalan, Anuradha, Chen, Zhenbang, Shaikh, Safa, Carracedo, Arkaitz, Alimonti, Andrea, Nardella, Caterina, Varmeh, Shohreh, Scardino, Peter T, Cordon-Cardo, Carlos, Gerald, William, Pandolfi, Pier Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835150/
https://ncbi.nlm.nih.gov/pubmed/19396168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.370
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