Genetic Manipulation of Tumor-specific Cytotoxic T Lymphocytes to Restore Responsiveness to IL-7

Adoptive transfer of antigen-specific cytotoxic T lymphocytes (CTLs) can induce objective clinical responses in patients with malignant diseases. The option of providing a proliferative and survival advantage to adoptively transferred CTLs remains a challenge to improve their efficacy. Host lymphode...

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Bibliographic Details
Main Authors: Vera, Juan F, Hoyos, Valentina, Savoldo, Barbara, Quintarelli, Concetta, Giordano Attianese, Greta MP, Leen, Ann M, Liu, Hao, Foster, Aaron E, Heslop, Helen E, Rooney, Cliona M, Brenner, Malcolm K, Dotti, Gianpietro
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835146/
https://ncbi.nlm.nih.gov/pubmed/19259067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.34
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