Genetic Manipulation of Tumor-specific Cytotoxic T Lymphocytes to Restore Responsiveness to IL-7

Adoptive transfer of antigen-specific cytotoxic T lymphocytes (CTLs) can induce objective clinical responses in patients with malignant diseases. The option of providing a proliferative and survival advantage to adoptively transferred CTLs remains a challenge to improve their efficacy. Host lymphode...

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Bibliografische gegevens
Hoofdauteurs: Vera, Juan F, Hoyos, Valentina, Savoldo, Barbara, Quintarelli, Concetta, Giordano Attianese, Greta MP, Leen, Ann M, Liu, Hao, Foster, Aaron E, Heslop, Helen E, Rooney, Cliona M, Brenner, Malcolm K, Dotti, Gianpietro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2009
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835146/
https://ncbi.nlm.nih.gov/pubmed/19259067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.34
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