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Genetic Manipulation of Tumor-specific Cytotoxic T Lymphocytes to Restore Responsiveness to IL-7

Adoptive transfer of antigen-specific cytotoxic T lymphocytes (CTLs) can induce objective clinical responses in patients with malignant diseases. The option of providing a proliferative and survival advantage to adoptively transferred CTLs remains a challenge to improve their efficacy. Host lymphode...

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מידע ביבליוגרפי
Main Authors: Vera, Juan F, Hoyos, Valentina, Savoldo, Barbara, Quintarelli, Concetta, Giordano Attianese, Greta MP, Leen, Ann M, Liu, Hao, Foster, Aaron E, Heslop, Helen E, Rooney, Cliona M, Brenner, Malcolm K, Dotti, Gianpietro
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835146/
https://ncbi.nlm.nih.gov/pubmed/19259067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.34
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