High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells

The cancer testis antigen (CTA) preferentially expressed antigen of melanoma (PRAME) is overexpressed by many hematologic malignancies, but is absent on normal tissues, including hematopoietic progenitor cells, and may therefore be an appropriate candidate for T cell–mediated immunotherapy. Because...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Quintarelli, Concetta, Dotti, Gianpietro, Hasan, Sayyeda T., De Angelis, Biagio, Hoyos, Valentina, Errichiello, Santa, Mims, Martha, Luciano, Luigia, Shafer, Jessica, Leen, Ann M., Heslop, Helen E., Rooney, Cliona M., Pane, Fabrizio, Brenner, Malcolm K., Savoldo, Barbara
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2011
נושאים:
Immunobiology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069675/
https://ncbi.nlm.nih.gov/pubmed/21278353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-300376
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים