High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells

The cancer testis antigen (CTA) preferentially expressed antigen of melanoma (PRAME) is overexpressed by many hematologic malignancies, but is absent on normal tissues, including hematopoietic progenitor cells, and may therefore be an appropriate candidate for T cell–mediated immunotherapy. Because...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Quintarelli, Concetta, Dotti, Gianpietro, Hasan, Sayyeda T., De Angelis, Biagio, Hoyos, Valentina, Errichiello, Santa, Mims, Martha, Luciano, Luigia, Shafer, Jessica, Leen, Ann M., Heslop, Helen E., Rooney, Cliona M., Pane, Fabrizio, Brenner, Malcolm K., Savoldo, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069675/
https://ncbi.nlm.nih.gov/pubmed/21278353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-300376
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker