High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells

The cancer testis antigen (CTA) preferentially expressed antigen of melanoma (PRAME) is overexpressed by many hematologic malignancies, but is absent on normal tissues, including hematopoietic progenitor cells, and may therefore be an appropriate candidate for T cell–mediated immunotherapy. Because...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Quintarelli, Concetta, Dotti, Gianpietro, Hasan, Sayyeda T., De Angelis, Biagio, Hoyos, Valentina, Errichiello, Santa, Mims, Martha, Luciano, Luigia, Shafer, Jessica, Leen, Ann M., Heslop, Helen E., Rooney, Cliona M., Pane, Fabrizio, Brenner, Malcolm K., Savoldo, Barbara
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2011
Θέματα:
Immunobiology
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069675/
https://ncbi.nlm.nih.gov/pubmed/21278353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-300376
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