Generation of Epstein-Barr virus–specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506)

Adoptive transfer of autologous Epstein-Barr virus–specific cytotoxic T lymphocytes (EBV-CTLs) to solid organ transplant (SOT) recipients has been shown safe and effective for the treatment of EBV-associated posttransplantation lymphoproliferative disorders (PTLDs). SOT recipients, however, require...

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Autors principals: De Angelis, Biagio, Dotti, Gianpietro, Quintarelli, Concetta, Huye, Leslie E., Zhang, Lan, Zhang, Ming, Pane, Fabrizio, Heslop, Helen E., Brenner, Malcolm K., Rooney, Cliona M., Savoldo, Barbara
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Gene Therapy
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786289/
https://ncbi.nlm.nih.gov/pubmed/19759356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-230482
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