Epstein Barr virus–specific cytotoxic T lymphocytes expressing the anti-CD30ζ artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease

Adoptive transfer of Epstein Barr virus (EBV)–specific cytotoxic T-lymphocytes (EBV-CTLs) has shown that these cells persist in patients with EBV(+) Hodgkin lymphoma (HD) to produce complete tumor responses. Treatment failure, however, occurs if a subpopulation of malignant cells in the tumor lacks...

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Bibliografiska uppgifter
Huvudupphovsmän: Savoldo, Barbara, Rooney, Cliona M., Di Stasi, Antonio, Abken, Hinrich, Hombach, Andreas, Foster, Aaron E., Zhang, Lan, Heslop, Helen E., Brenner, Malcolm K., Dotti, Gianpietro
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2007
Ämnen:
Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988944/
https://ncbi.nlm.nih.gov/pubmed/17507664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-059139
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