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Age-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double knock-in mice: Relevance to Alzheimer disease
Using APP(NLh)/APP(NLh)×PS-1(P246L)/PS-1(P246L) human double knock-in (APP/PS-1) mice, we examined whether phosphatidylserine (PtdSer) asymmetry is significantly altered in brain of this familial Alzheimer disease mouse model in an age-dependent manner as a result of oxidative stress, toxic Aβ(1–42)...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834848/ https://ncbi.nlm.nih.gov/pubmed/20083199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.01.004 |
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