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Oxidative damage in brain from human mutant APP/PS-1 double knock-in mice as a function of age

Oxidative stress is strongly implicated in the progressive decline of cognition associated with aging and neurodegenerative disorders. In the brain, free radical-mediated oxidative stress plays a critical role in the age-related decline of cellular function as a result of the oxidation of proteins,...

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Detalhes bibliográficos
Main Authors: Abdul, Hafiz Mohmmad, Sultana, Rukhsana, St. Clair, Daret K., Markesbery, William R., Butterfield, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597707/
https://ncbi.nlm.nih.gov/pubmed/18762245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.08.012
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