Advanced Glycation End-Products Induce Tubular CTGF via TGF-β–Independent Smad3 Signaling

Advanced glycation end-products (AGEs) can induce expression of connective tissue growth factor (CTGF), which seems to promote the development of diabetic nephropathy, but the exact signaling mechanisms that mediate this induction are unknown. Here, AGEs induced CTGF expression in tubular epithelial...

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Bibliografski detalji
Glavni autori: Chung, Arthur C.K., Zhang, Haiyan, Kong, Yao-Zhong, Tan, Jia-Ju, Huang, Xiao R., Kopp, Jeffrey B., Lan, Hui Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2010
Teme:
Basic Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834552/
https://ncbi.nlm.nih.gov/pubmed/19959709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009010018
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