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miR-192 Mediates TGF-β/Smad3-Driven Renal Fibrosis
TGF-β/Smad3 promotes renal fibrosis, but the mechanisms that regulate profibrotic genes remain unclear. We hypothesized that miR-192, a microRNA expressed in the kidney may mediate renal fibrosis in a Smad3-dependent manner. Microarray and real-time PCR demonstrated a tight association between upreg...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938591/ https://ncbi.nlm.nih.gov/pubmed/20488955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010020134 |
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