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Advanced Glycation End-Products Induce Tubular CTGF via TGF-β–Independent Smad3 Signaling
Advanced glycation end-products (AGEs) can induce expression of connective tissue growth factor (CTGF), which seems to promote the development of diabetic nephropathy, but the exact signaling mechanisms that mediate this induction are unknown. Here, AGEs induced CTGF expression in tubular epithelial...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Nephrology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834552/ https://ncbi.nlm.nih.gov/pubmed/19959709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009010018 |
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