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Advanced Glycation End-Products Induce Tubular CTGF via TGF-β–Independent Smad3 Signaling

Advanced glycation end-products (AGEs) can induce expression of connective tissue growth factor (CTGF), which seems to promote the development of diabetic nephropathy, but the exact signaling mechanisms that mediate this induction are unknown. Here, AGEs induced CTGF expression in tubular epithelial...

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Detalhes bibliográficos
Main Authors: Chung, Arthur C.K., Zhang, Haiyan, Kong, Yao-Zhong, Tan, Jia-Ju, Huang, Xiao R., Kopp, Jeffrey B., Lan, Hui Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834552/
https://ncbi.nlm.nih.gov/pubmed/19959709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009010018
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