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Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs
Blockade of transforming growth factor-β (TGF-β) signaling by Smad7 gene therapy is known to prevent experimental renal fibrosis. This study investigated whether Smad7 suppresses renal fibrosis via altering the renal expression of fibrosis-related microRNAs. Application of gene therapy into diseased...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594008/ https://ncbi.nlm.nih.gov/pubmed/23207693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.251 |
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