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Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs

Blockade of transforming growth factor-β (TGF-β) signaling by Smad7 gene therapy is known to prevent experimental renal fibrosis. This study investigated whether Smad7 suppresses renal fibrosis via altering the renal expression of fibrosis-related microRNAs. Application of gene therapy into diseased...

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Détails bibliographiques
Auteurs principaux: Chung, Arthur C.K., Dong, Yuan, Yang, Weiqin, Zhong, Xiang, Li, Rong, Lan, Hui Y.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594008/
https://ncbi.nlm.nih.gov/pubmed/23207693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.251
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