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Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics
Furin belongs to the family of proprotein convertases (PCs) and is involved in numerous normal physiological and pathogenic processes, such as viral propagation, bacterial toxin activation, cancer and metastasis. Furin and related furin-like PCs cleave their substrates at characteristic multibasic c...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834293/ https://ncbi.nlm.nih.gov/pubmed/20038105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9012455 |
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