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A competitive inhibitor traps LeuT in an open-to-out conformation

Secondary transporters are workhorses of cellular membranes, catalyzing the movement of small molecules and ions across the bilayer, coupling substrate passage to ion gradients. However, the conformational changes that accompany substrate transport, the mechanism by which substrate moves through the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Singh, Satinder K., Piscitelli, Chayne L., Yamashita, Atsuko, Gouaux, Eric
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832577/
https://ncbi.nlm.nih.gov/pubmed/19074341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1166777
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