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A competitive inhibitor traps LeuT in an open-to-out conformation
Secondary transporters are workhorses of cellular membranes, catalyzing the movement of small molecules and ions across the bilayer, coupling substrate passage to ion gradients. However, the conformational changes that accompany substrate transport, the mechanism by which substrate moves through the...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832577/ https://ncbi.nlm.nih.gov/pubmed/19074341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1166777 |
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