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Neurotransmitter/sodium symporter orthologue LeuT has a single high–affinity substrate site

Neurotransmitter/sodium symporters (NSSs) couple the uptake of neurotransmitter with one or more sodium ions(1–3), removing neurotransmitter from the synaptic cleft. NSSs are essential to the function of chemical synapses, are associated with multiple neurological diseases and disorders(4), and are...

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Detalhes bibliográficos
Main Authors: Piscitelli, Chayne L., Krishnamurthy, Harini, Gouaux, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079577/
https://ncbi.nlm.nih.gov/pubmed/21179170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09581
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