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Insights into transport mechanism from LeuT engineered to transport tryptophan

LeuT is a bacterial homologue of the neurotransmitter:sodium symporter (NSS) family and, being the only NSS member to have been structurally characterized by X-ray crystallography, is a model protein for studying transporter structure and mechanism. Transport activity in LeuT was hypothesized to req...

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Autori principali: Piscitelli, Chayne L, Gouaux, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252571/
https://ncbi.nlm.nih.gov/pubmed/21952050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.353
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