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Conformational Rearrangements to the Intracellular Open States of the LeuT and ApcT Transporters Are Modulated by Common Mechanisms

Recent crystallographic studies revealed that five transporter families without much sequence similarities among them have similar structure folds to LeuT, a bacterial neurotransmitter:sodium symporter homolog. The LeuT fold is characterized by an internal twofold structural pseudosymmetry. The tran...

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Detalhes bibliográficos
Main Authors: Shi, Lei, Weinstein, Harel
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000488/
https://ncbi.nlm.nih.gov/pubmed/21156121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.003
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