Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation

Runx1 is a key hematopoietic transcription factor required for definitive hematopoiesis and is a frequent target of leukemia-related chromosomal translocations. The resulting fusion proteins, while retaining DNA binding activity, display loss of subnuclear targeting and associated transactivation fu...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Dowdy, Christopher R., Xie, Ronglin, Frederick, Dana, Hussain, Sadiq, Zaidi, Sayyed K., Vradii, Diana, Javed, Amjad, Li, Xiangen, Jones, Stephen N., Lian, Jane B., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830828/
https://ncbi.nlm.nih.gov/pubmed/20035012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp568
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker