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Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription
Src/Yes tyrosine kinase signaling contributes to the regulation of bone homeostasis and inhibits osteoblast activity. Here we show that the endogenous Yes-associated protein (YAP), a mediator of Src/Yes signaling, interacts with the native Runx2 protein, an osteoblast-related transcription factor, a...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2004
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC380991/ https://ncbi.nlm.nih.gov/pubmed/14765127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600073 |
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