Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses

Lignende værker

• A Substructure Combination Strategy to Create Potent and Selective Transthyretin Kinetic Stabilizers that Prevent Amyloidogenesis and Cytotoxicity
  af: Choi, Sungwook, et al.
  Udgivet: (2010)
• The Transthyretin Amyloidoses: From Delineating the Molecular Mechanism of Aggregation Linked to Pathology to a Regulatory Agency Approved Drug
  af: Johnson, Steven M., et al.
  Udgivet: (2012)
• Towards optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies
  af: Johnson, Steven M., et al.
  Udgivet: (2008)
• Potent Kinetic Stabilizers that Prevent Transthyretin-mediated Cardiomyocyte Proteotoxicity
  af: Alhamadsheh, Mamoun M., et al.
  Udgivet: (2011)
• Toward Optimization of the Second Aryl Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies
  af: Johnson, Steven M., et al.
  Udgivet: (2009)