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Dynamics of the β(2)-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange
To examine the molecular details of ligand activation of G-protein coupled receptor (GPCRs), emphasis has been placed on structure determination of these receptors with stabilizing ligands. Here we present the methodology for receptor dynamics characterization of the GPCR human β(2) adrenergic recep...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829980/ https://ncbi.nlm.nih.gov/pubmed/20058880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac902484p |
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