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Molecular dosimetry of 1, 2, 3, 4-diepoxybutane induced DNA-DNA crosslinks in B6C3F1 mice and F344 rats exposed to 1,3-butadiene by inhalation
1,3-butadiene (BD) is an important industrial and environmental chemical classified as a human carcinogen based on epidemiological studies in occupationally exposed workers and animal studies in laboratory rats and mice. BD is metabolically activated to three epoxides that can react with nucleophili...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828062/ https://ncbi.nlm.nih.gov/pubmed/19276346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4152 |
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