CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis

Ewing sarcoma (EWS) is an aggressive bone tumor of uncertain cellular origin. CD99 is a membrane protein that is expressed in most cases of EWS, although its function in the disease is unknown. Here we have shown that endogenous CD99 expression modulates EWS tumor differentiation and malignancy. We...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rocchi, Anna, Manara, Maria Cristina, Sciandra, Marika, Zambelli, Diana, Nardi, Filippo, Nicoletti, Giordano, Garofalo, Cecilia, Meschini, Stefania, Astolfi, Annalisa, Colombo, Mario P., Lessnick, Stephen L., Picci, Piero, Scotlandi, Katia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827943/
https://ncbi.nlm.nih.gov/pubmed/20197622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36667
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