Identification of Common and Distinctive Mechanisms of Resistance to Different Anti-IGF-IR Agents in Ewing's Sarcoma

IGF system contributes significantly to many human malignancies. Targeting IGF-I receptor (IGF-IR) has been reported to be active against several tumors, but particular efficacy was observed only against a minority of Ewing's sarcoma patients. Identification of mechanisms of acquired resistance...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Endocrinol
Autori principali: Garofalo, Cecilia, Mancarella, Caterina, Grilli, Andrea, Manara, Maria Cristina, Astolfi, Annalisa, Marino, Maria Teresa, Conte, Alexia, Sigismund, Sara, Carè, Alessandra, Belfiore, Antonino, Picci, Piero, Scotlandi, Katia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2012
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416976/
https://ncbi.nlm.nih.gov/pubmed/22798295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1142
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