Exosomes from CD99-deprived Ewing sarcoma cells reverse tumor malignancy by inhibiting cell migration and promoting neural differentiation

Ewing sarcoma (EWS) is an aggressive mesenchymal tumor with unmet clinical need and significant social impacts on children, adolescents, and young adults. CD99, a hallmark surface molecule of EWS, participates in crucial biological processes including cell migration, differentiation, and death. EWS...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: De Feo, Alessandra, Sciandra, Marika, Ferracin, Manuela, Felicetti, Federica, Astolfi, Annalisa, Pignochino, Ymera, Picci, Piero, Carè, Alessandra, Scotlandi, Katia
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572819/
https://ncbi.nlm.nih.gov/pubmed/31209202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1675-1
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