Exosomes from CD99-deprived Ewing sarcoma cells reverse tumor malignancy by inhibiting cell migration and promoting neural differentiation

Ewing sarcoma (EWS) is an aggressive mesenchymal tumor with unmet clinical need and significant social impacts on children, adolescents, and young adults. CD99, a hallmark surface molecule of EWS, participates in crucial biological processes including cell migration, differentiation, and death. EWS...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: De Feo, Alessandra, Sciandra, Marika, Ferracin, Manuela, Felicetti, Federica, Astolfi, Annalisa, Pignochino, Ymera, Picci, Piero, Carè, Alessandra, Scotlandi, Katia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572819/
https://ncbi.nlm.nih.gov/pubmed/31209202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1675-1
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