Map4k4 Negatively Regulates Peroxisome Proliferator-activated Receptor (PPAR) γ Protein Translation by Suppressing the Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Cultured Adipocytes

The receptor peroxisome proliferator-activated receptor γ (PPARγ) is considered a master regulator of adipocyte differentiation and promotes glucose and lipid metabolism in mature adipocytes. We recently identified the yeast Sterile 20 (Ste20) protein kinase ortholog, Map4k4, in an RNA interference-...

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Detalhes bibliográficos
Main Authors: Guntur, Kalyani V. P., Guilherme, Adilson, Xue, Liting, Chawla, Anil, Czech, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825455/
https://ncbi.nlm.nih.gov/pubmed/20038583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068502
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