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Tumor Necrosis Factor-α Induces Caspase-mediated Cleavage of Peroxisome Proliferator-activated Receptor γ in Adipocytes

The nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-dependent transcription factor that acts as a primary regulator of adipogenesis and controls adipocyte metabolism and insulin action. Increased expression of tumor necrosis factor (TNFα) in adipose tissue of obese...

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Bibliografiske detaljer
Main Authors: Guilherme, Adilson, Tesz, Gregory J., Guntur, Kalyani V. P., Czech, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719346/
https://ncbi.nlm.nih.gov/pubmed/19321447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809042200
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