Amyloid-β-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Aβ peptide. Implications for the pathogenesis of Alzheimer's disease

The presence of amyloid-β (Aβ) deposits in selected brain regions is a hallmark of Alzheimer's disease (AD). The amyloid deposits have "chaperone molecules" which play critical roles in amyloid formation and toxicity. We report here that treatment of rat hippocampal neurons with Aβ-ac...

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Detalhes bibliográficos
Main Authors: Dinamarca, Margarita C, Sagal, Juan P, Quintanilla, Rodrigo A, Godoy, Juan A, Arrázola, Macarena S, Inestrosa, Nibaldo C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823746/
https://ncbi.nlm.nih.gov/pubmed/20205793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-4
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