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Amyloid-β-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Aβ peptide. Implications for the pathogenesis of Alzheimer's disease

The presence of amyloid-β (Aβ) deposits in selected brain regions is a hallmark of Alzheimer's disease (AD). The amyloid deposits have "chaperone molecules" which play critical roles in amyloid formation and toxicity. We report here that treatment of rat hippocampal neurons with Aβ-ac...

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書誌詳細
主要な著者: Dinamarca, Margarita C, Sagal, Juan P, Quintanilla, Rodrigo A, Godoy, Juan A, Arrázola, Macarena S, Inestrosa, Nibaldo C
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823746/
https://ncbi.nlm.nih.gov/pubmed/20205793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-4
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