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β-Amyloid: the key peptide in the pathogenesis of Alzheimer’s disease

The amyloid β peptide (Aβ) is a critical initiator that triggers the progression of Alzheimer’s Disease (AD) via accumulation and aggregation, of which the process may be caused by Aβ overproduction or perturbation clearance. Aβ is generated from amyloid precursor protein through sequential cleavage...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Sun, Xiaojuan, Chen, Wei-Dong, Wang, Yan-Dong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588032/
https://ncbi.nlm.nih.gov/pubmed/26483691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00221
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