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β-Amyloid: the key peptide in the pathogenesis of Alzheimer’s disease

The amyloid β peptide (Aβ) is a critical initiator that triggers the progression of Alzheimer’s Disease (AD) via accumulation and aggregation, of which the process may be caused by Aβ overproduction or perturbation clearance. Aβ is generated from amyloid precursor protein through sequential cleavage...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Sun, Xiaojuan, Chen, Wei-Dong, Wang, Yan-Dong
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588032/
https://ncbi.nlm.nih.gov/pubmed/26483691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00221
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