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Metabolism of amyloid β peptide and pathogenesis of Alzheimer’s disease

The conversion of what has been interpreted as “normal brain aging” to Alzheimer’s disease (AD) via transition states, i.e., preclinical AD and mild cognitive impairment, appears to be a continuous process caused primarily by aging-dependent accumulation of amyloid β peptide (Aβ) in the brain. This...

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Bibliographic Details
Main Author: SAIDO, Takaomi C.
Format: Artigo
Language:Inglês
Published: The Japan Academy 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758963/
https://ncbi.nlm.nih.gov/pubmed/23883611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.89.321
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