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Metabolism of amyloid β peptide and pathogenesis of Alzheimer’s disease

The conversion of what has been interpreted as “normal brain aging” to Alzheimer’s disease (AD) via transition states, i.e., preclinical AD and mild cognitive impairment, appears to be a continuous process caused primarily by aging-dependent accumulation of amyloid β peptide (Aβ) in the brain. This...

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Detalhes bibliográficos
Autor principal: SAIDO, Takaomi C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Japan Academy 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758963/
https://ncbi.nlm.nih.gov/pubmed/23883611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.89.321
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