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Dual roles for autophagy: Degradation and secretion of Alzheimer's disease Aβ peptide
Alzheimer's disease (AD) is a neurodegenerative disease exhibiting amyloid beta (Aβ) peptide accumulation as a key characteristic. Autophagy, which is dysregulated in AD, participates in the metabolism of Aβ. Unexpectedly, we recently found that autophagy, in addition to its degradative functio...
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| Publicado no: | Bioessays |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4316186/ https://ncbi.nlm.nih.gov/pubmed/24711225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201400002 |
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