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Aβ Secretion and Plaque Formation Depend on Autophagy
Alzheimer’s disease (AD) is a neurodegenerative disease biochemically characterized by aberrant protein aggregation, including amyloid beta (Aβ) peptide accumulation. Protein aggregates in the cell are cleared by autophagy, a mechanism impaired in AD. To investigate the role of autophagy in Aβ patho...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2013-10-01
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| Series: | Cell Reports |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S2211124713005020 |
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