Llwytho...

Modulation of the cold-activated cation channel TRPM8 by surface charge screening

TRPM8, a cation channel activated by cold and by cooling agents such as menthol and icilin, is critically involved in somatosensory cold sensation. Ion fluxes through TRPM8 are highly sensitive to changes in extracellular Ca(2+) and pH, but the mechanisms underlying this type of modulation are poorl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mahieu, Frank, Janssens, Annelies, Gees, Maarten, Talavera, Karel, Nilius, Bernd, Voets, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821726/
https://ncbi.nlm.nih.gov/pubmed/19948654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.183582
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