The Ca(2+)-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate

Transient receptor potential (TRP) channel, melastatin subfamily (TRPM)4 is a Ca(2+)-activated monovalent cation channel that depolarizes the plasma membrane and thereby modulates Ca(2+) influx through Ca(2+)-permeable pathways. A typical feature of TRPM4 is its rapid desensitization to intracellula...

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Bibliographic Details
Main Authors: Nilius, Bernd, Mahieu, Frank, Prenen, Jean, Janssens, Annelies, Owsianik, Grzegorz, Vennekens, Rudi, Voets, Thomas
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383543/
https://ncbi.nlm.nih.gov/pubmed/16424899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600963
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