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Agonist-Induced Changes in Ca(2+) Permeation through the Nociceptor Cation Channel TRPA1

The Ca(2+)-permeable cation channel TRPA1 acts as an ionotropic receptor for various pungent compounds and as a noxious cold sensor in sensory neurons. It is unclear what proportion of the TRPA1-mediated current is carried by Ca(2+) ions and how the permeation pathway changes during stimulation. Her...

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Detalhes bibliográficos
Main Authors: Karashima, Yuji, Prenen, Jean, Talavera, Karel, Janssens, Annelies, Voets, Thomas, Nilius, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830466/
https://ncbi.nlm.nih.gov/pubmed/20197030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.007
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