Decavanadate modulates gating of TRPM4 cation channels

We have tested the effects of decavanadate (DV), a compound known to interfere with ATP binding in ATP-dependent transport proteins, on TRPM4, a Ca(2+)-activated, voltage-dependent monovalent cation channel, whose activity is potently blocked by intracellular ATP(4−). Application of micromolar Ca(2+...

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Detalhes bibliográficos
Main Authors: Nilius, Bernd, Prenen, Jean, Janssens, Annelies, Voets, Thomas, Droogmans, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665285/
https://ncbi.nlm.nih.gov/pubmed/15331675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.070839
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