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Treatment Strategies Targeting Excess Hippocampal Activity Benefit Aged Rats with Cognitive Impairment

Excess neural activity in the CA3 region of the hippocampus has been linked to memory impairment in aged rats. We tested whether interventions aimed at reducing this excess activity would improve memory performance. Aged (24 to 28 months old) male Long–Evans rats were characterized in a spatial memo...

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Bibliografische gegevens
Hoofdauteurs: Koh, Ming Teng, Haberman, Rebecca P, Foti, Stacey, McCown, Thomas J, Gallagher, Michela
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820138/
https://ncbi.nlm.nih.gov/pubmed/20032967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.207
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