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Selective GABA(A) α5 Positive Allosteric Modulators Improve Cognitive Function in Aged Rats with Memory Impairment

A condition of excess activity in the hippocampal formation is observed in the aging brain and in conditions that confer additional risk during aging for Alzheimer’s disease. Compounds that act as positive allosteric modulators at GABA(A) α5 receptors might be useful in targeting this condition beca...

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Detalhes bibliográficos
Main Authors: Koh, Ming Teng, Rosenzweig-Lipson, Sharon, Gallagher, Michela
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445657/
https://ncbi.nlm.nih.gov/pubmed/22732440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.06.023
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