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Selective GABA(A) α5 Positive Allosteric Modulators Improve Cognitive Function in Aged Rats with Memory Impairment
A condition of excess activity in the hippocampal formation is observed in the aging brain and in conditions that confer additional risk during aging for Alzheimer’s disease. Compounds that act as positive allosteric modulators at GABA(A) α5 receptors might be useful in targeting this condition beca...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445657/ https://ncbi.nlm.nih.gov/pubmed/22732440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.06.023 |
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