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Significance of inhibitory recruitment in aging with preserved cognition: limiting gamma-aminobutyric acid type A α5 function produces memory impairment

Numerous aging studies have identified a shift in the excitatory/inhibitory (E/I) balance with heightened hippocampal neural activity associated with age-related memory impairment across species, including rats, monkeys, and humans. Neurobiological investigations directed at the hippocampal formatio...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Koh, Ming Teng, Branch, Audrey, Haberman, Rebecca, Gallagher, Michela
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641038/
https://ncbi.nlm.nih.gov/pubmed/32240868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.02.019
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